Jianjun Liu, PhD

Deputy Executive Director at the Genome Institute of Singapore (GIS)

Professor at the Yong Loo Lin School of Medicine, National University of Singapore

Email: liuj3@gis.a-star.edu.sg


Prof Liu did his undergraduated study at the University of Science and Technology of China, got his Master degree from the Institute of Oceanology at the Chinese Academy of Science and was awarded PhD degree on quantitative genetics at the Duke University. He did his postdoctoral training on the genetics of psychiatric disorders at the Columbia University and joined GIS as a faculty in 2002.

The main research interest of Prof Liu’s lab is to understand the genetic basis of human diseases .Mainly focusing on complex disease related phenotypes, his lab pursues collaborative research to discover genetic variants that influence disease susceptibility, progression and treatment outcome. Largely working on Asian populations, he researches on diverse disease phenotypes, including cancers, autoimmune/ inflammatory diseases, neurological/neurosychiatric disorders, metabolic and cardiovascular diseases, and infectious diseases and has discovered many novel disease susceptibility genes. Prof Liu’s research also covers pharmacogenomics, particularly the discovery of biomarkers for adverse drug reactions (ADRs) in Asian populations. Recently, Prof Liu has expanded his research to population genomics, for example, the SG10K project where 10,000 Singaporeans are being subjected to whole genome sequencing (WGS) analysis. Population genomics are driving precision medicine programs around the world to explore the application of large-scale genomic and omic data in improving clinical and health services. In addition, Prof Liu’s lab is also exploring genome-genome interaction analysis, for example, to understand pathogen-host interaction in infectious diseases as well as germline-somatic mutation interaction in cancer development.

By publishing over 300 peer reviewed papers, Prof Liu has been well recognized by international research community. According to the information from Google Scholar Citations database (reported by the Consejo Superior de Investigaciones Cientificas (CSIC) in April 2019), Prof Liu was ranked as one of top 2000 scientists with highest citations (H-index 116, citations > 70,000) around the world. He has won the “Chen Young Investigator Award” from the Human Genome Organization (HUGO) in 2011 and been recognized by Thomson Reuters as one of “The World’s Most Influential Scientific Minds” (top 1% of scientists with the highest number of citations globally) in 2015.